Aflatoxin G1

Aflatoxin G1 is a mycotoxin that has been found in A. terricola.{57298} In vivo, aflatoxin G1 is lethal to ducklings (LD50 = 1.18 mg/kg).{57299} It induces hepatocellular carcinoma tumor formation and lethality in rats when administered at doses of 1.4 and 3 mg/animal, respectively. Aflatoxin G1 also inhibits liver and kidney succinate dehydrogenase and fumarase, as well as kidney cytochrome oxidase, NADH oxidase, a-glycerophosphate dehydrogenase, isocitrate dehydrogenase, and malate dehydrogenase in rats.{57300}