Product description
CD11c (p150, alphaX integrin subunit) forms complex with CD18 (beta2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other beta2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b.
Specifications
Applications
FC, IP, IHC-Fr
Host
Mouse
Clonality
Monoclonal
Clone
BU15
Isotype
Mouse IgG1
Supplier
Exbio
Shipping & storage
Storage temperature
2-8°C

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Mouse Monoclonal to CD11c, Clone BU15, purified

11-529-C100

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Productname

Mouse Monoclonal to CD11c, Clone BU15, purified

11-529-C100

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