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Mouse Monoclonal to SHIP-1, Clone SHIP-01, purified
11-524-C100
0,1 mg
€193
Product description
SHIP-1 (SH2 domain containing inositol phosphatase-1) is a 5´inositol phosphatase that regulates cell responses in lymphocytes and myeloid cells by hydrolyzing the second messenger PI(3,4,5) trisphosphate. SHIP-1 is recruited upon engagement of both inhibitory and activatory receptors, such as FcgammaRIIB, Fcgamma RIII, FcepsilonRI or cytokine and growth factor receptors, and supresses PI3K-dependent signaling, down-regulates cell migration and invasion of transformed cells and phagocytosis. SHIP-1 also serves as a scaffold for the recruitment of other proteins to the plasma membrane.
Specifications
Applications
FC, WB
Host
Mouse
Clonality
Monoclonal
Clone
SHIP-01
Isotype
Mouse IgG2a
Supplier
Exbio
Shipping & storage
Storage temperature
2-8°C
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Productname
Mouse Monoclonal to SHIP-1, Clone SHIP-01, purified
11-524-C100
By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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Productname
Mouse Monoclonal to SHIP-1, Clone SHIP-01, purified
11-524-C100
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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