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Mouse Monoclonal to Daxx / DAP6, Clone DAXX-03, purified
11-517-C100
0,1 mg
€193
Product description
Daxx is an apoptosis-modulating death domain-associated protein with functions in transcriptional regulation. Daxx functions both in cytoplasm, where it interacts with Fas, and in nucleus (residing in PML oncogenic domains), where it is involved in SUMO-dependent regulation of transcription and subnuclear compartmentalization. Daxx senzitizes the cells to apoptosis, but on the other hand, this protein may also serve in preventing apoptosis in the early embryo. Even regarding the transcription, Daxx can serve both as a corepressor and a coactivator. During ischemic stress, Daxx translocates from the nucleus to the cytoplasm, where in regulates sodium hydrogen exchanger isoform 1 (NHE1).
Specifications
Applications
IP, WB, ICC
Host
Mouse
Clonality
Monoclonal
Clone
DAXX-03
Isotype
Mouse IgG1
Supplier
Exbio
Shipping & storage
Storage temperature
2-8°C
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Productname
Mouse Monoclonal to Daxx / DAP6, Clone DAXX-03, purified
11-517-C100
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Productname
Mouse Monoclonal to Daxx / DAP6, Clone DAXX-03, purified
11-517-C100
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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