Product description
STIM1 (stromal interacting molecule; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane. Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm. However, the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet. Many questions also remain to be solved around STIM1 functional distribution. It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.
Specifications
Applications
IP, IHC-P, WB, ICC
Host
Mouse
Clonality
Monoclonal
Clone
CDN3H4
Isotype
Mouse IgG1
Supplier
Exbio
Shipping & storage
Storage temperature
2-8°C

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Productname

Mouse Monoclonal to STIM1 / GOK, Clone CDN3H4, purified

11-497-C100

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Productname

Mouse Monoclonal to STIM1 / GOK, Clone CDN3H4, purified

11-497-C100

By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


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