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Anti-p21Waf1 Purified
11-338-C100
0,1 mg
€193
Product description
The tumour suppressor p21Waf1 (wild-type p53-activated fragment 1; also known as Cip1, Cdk interacting protein, or SDI 1) is a cyclin-dependent kinase (Cdk) inhibitor, which is expressed by involvement of p53, Egr-1, AP2, STATs or other transcription factors upon various stimuli resulting in cell cycle arrest. Through its N-terminal domain p21Waf1 inhibits Cdk activity, whereas through the C-terminal domain it inhibits the activity of PCNA (proliferating cell nuclear antigen) to activate DNA replication. Cytosolic location of p21 counteracts its inhibitory activities.
Specifications
Applications
IHC-P, ELISA, ICC
Host
Mouse
Clonality
Monoclonal
Clone
WA-1
Isotype
Mouse IgG1
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
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Anti-p21Waf1 Purified
11-338-C100
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Anti-p21Waf1 Purified
11-338-C100
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