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Mouse Monoclonal to CD72, Clone 3F3, purified
11-310-C100
0,1 mg
€167
Product description
CD72 is a transmembrane glycoprotein expressed as a homodimer especially in B cells, but also in other antigen presenting cells such as dendritic cells and macrophages. Through one of its immunoreceptor tyrosine-based inhibitory motives (ITIMs), CD72 interacts with tyrosine phosphatase SHP-1, thereby suppressing B cell responsiveness. Binding of CD72 with its ligand CD100 (Sema4D) prevents BCR association and phosphorylation of CD72 and results in dissociation of SHP-1 from CD72, thus enables B cell activation.
Specifications
Applications
FC, IP
Host
Mouse
Clonality
Monoclonal
Clone
3F3
Isotype
Mouse IgG2b
Supplier
Exbio
Shipping & storage
Storage temperature
2-8°C
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Productname
Mouse Monoclonal to CD72, Clone 3F3, purified
11-310-C100
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Productname
Mouse Monoclonal to CD72, Clone 3F3, purified
11-310-C100
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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