Product description
CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.
Specifications
Applications
FC, IP, IHC-P, WB
Host
Mouse
Clonality
Monoclonal
Clone
MEM-98
Isotype
Mouse IgG1
Supplier
Exbio
Shipping & storage
Storage temperature
2-8°C

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Mouse Monoclonal to CD6, Clone MEM-98, purified

11-205-C100

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Productname

Mouse Monoclonal to CD6, Clone MEM-98, purified

11-205-C100

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