Product description
Clofibrate is a selective agonist of peroxisome proliferator-activated receptor a (PPARa).{10670} In a transactivation assay, clofibrate exhibits EC50 values of 50 and 55 µM for murine and human PPARa, respectively. It also binds to PPARy but with 10-fold less affinity and is inactive at PPARd at concentrations up to 100 µM. Formulations containing clofibrate have been used to treat dyslipidemia and cardiovascular disease.
Specifications
CAS number
637-07-0
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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