15-keto-17-phenyl trinor Prostaglandin F2a ethyl amide

Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2a ethyl amide (17-phenyl trinor PGF2a ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug.{8941} Oxidation of the C-15 hydroxyl group produces 15-keto-17-phenyl trinor PGF2a ethyl amide. 15-keto-17-phenyl trinor PGF2a ethyl amide is a potential metabolite of 17-phenyl trinor PGF2a ethyl amide when 17-phenyl trinor PGF2a ethyl amide is administered to intact animals. No pharmacological studies on 15-keto-17-phenyl trinor PGF2a ethyl amide have been reported.