Product description
Prostaglandin F2a (PGF2a) drives luteolysis and smooth muscle contraction by activating the FP receptor. Stable, lipophilic analogs of PGF2a are used to modulate luteolysis and treat glaucoma. 16-phenoxy tetranor Prostaglandin F2a (16-phenoxy tetranor PGF2a) is a metabolically stable form of PGF2a containing a 16-phenoxy group at the w-terminus. It binds to the FP receptor on ovine luteal cells with much greater affinity (440%) than PGF2a.{2058} 16-phenoxy tetranor PGF2a methyl ester is a lipophilic analog of 16-phenoxy tetranor PGF2a. Methyl esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.
Specifications
CAS number
51638-90-5
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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16-phenoxy tetranor Prostaglandin F2a methyl ester

10010102-1

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16-phenoxy tetranor Prostaglandin F2a methyl ester

10010102-1

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