Product description
(+)-Nutlin-3 is the enantiomer and less active form of the p53-Mdm2 protein-protein interaction inhibitor (-)-nutlin-3 (Item No. 18585).{11628} It inhibits the interaction between p53 and Mdm2 150-fold less potently than (-)-nutlin-3 with an IC50 value of 13.6 µM. (+)-Nutlin-3 has been used as a negative control for the p53-modulating activity of (-)-nutlin-3 in cancer cells.
Specifications
CAS number
675576-97-3
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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(+)-Nutlin-3

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(+)-Nutlin-3

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