Product description
2,3-bis(4-Hydroxyphenyl)propionitrile (DPN) is an estrogen receptor B (ERB) selective agonist. DPN exhibits a 70-fold higher relative binding affinity for ERB (18%) versus ERa (0.25%), about 80-fold higher transcriptional potency (EC50 = 0.85 nM versus 66 nM), and 170-fold higher relative potency (4.6% versus 0.025%) in transcription assays.{14165} Based on this selectivity, DPN is commonly used as a tool to evaluate the biological role of ERB.
Specifications
CAS number
1428-67-7
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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2,3-bis (4-Hydroxyphenyl) Propionitrile

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2,3-bis (4-Hydroxyphenyl) Propionitrile

10008842-10

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