13,14-dihydro-15-keto Prostaglandin F2a-d4

13,14-dihydro-15-keto Prostaglandin F2a-d4 (13,14-dihydro-15-keto PGF2a-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 13,14-dihydro-15-keto PGF2a by GC- or LC-mass spectrometry. 13,14-dihydro-15-keto PGF2a is the first prominent plasma metabolite of PGF2a in the 15-hydroxy PGDH pathway.{187} Measurement of 13,14-dihydro-15-keto PGF2a in plasma can be used as a marker of the in vivo production of PGF2a.{187,878,1463}