Product description
Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2.{1410} In rats and rabbits, 2,3-dinor TXB1 has been identified as another urinary metabolite of TXB2.{12600,12599} However in human urine, only trace amounts of 2,3-dinor TXB1 have been identified.{12600} In rats, 2,3-dinor TXB1 is excreted at a much higher rate than 2,3-dinor TXB2 (19.2 +- 4.9 ng/24 hr and 1.6 +- 0.3 ng/24 hr, respectively).{12600} Therefore, urinary 2,3-dinor TXB1 is a suitable marker of thromboxane biosynthesis in rats.
Specifications
CAS number
196493-76-2
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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2,3-dinor Thromboxane B1

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