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CAY10443
10004177-10
10 mg
€113
Product description
Mitochondrial release of cytochrome c triggers apoptosis via the assembly of a multimeric complex including caspase-9, Apaf-1, and other components, sometimes called the apoptosome.{6873} Library screens have identified small molecules that activate the apoptosome by binding to one or more of its components. CAY10443 is one such molecule. In a cell free, multi-component assay, it activated caspase-3 with an EC50 of 5 µM.{11535} These apoptotic activators represent therapeutic lead compounds for the development of antitumor drugs.
Specifications
CAS number
582314-48-5
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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10004177-10
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10004177-10
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