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Multiplex Assay for KRAS mutations
The Signature® KRAS Mutations 7 (RUO*) assay, by Asuragen, is based on the Signature® Technology Platform for the rapid multiplex analysis of nucleic acid sequences, allowing detection of up to 100 DNA or RNA targets in a single reaction well. The Signature® KRAS Mutations (RUO*) provides comprehensive information on 7 distinct mutations within codons 12 and 13 of the KRAS oncogene. The 96-well assay format enables characterization of KRAS mutation status in approximately 4 hours using a broad input range of genomic DNA isolated from cultured cells or fresh, frozen or formalin-fixed paraffin-embedded (FFPE) specimens. The streamlined workflow and multiplex assay format increase specimen throughput, decrease reagents/supplies use and reaction set up time, and overall, reduce the cost per individual mutation tested.
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SP Rabbit Monoclonal Antibodies
Spring has an interesting and expanding menu of rabbit monoclonal antibodies that are especially designed and characterized for use in immunohistochemistry (IHC). Spring was one of the first companies to introduce these products to the IHC market, and over the years Spring's SP clones have developed a gold-standard reputation in the IHC laboratory.
Spring is a biotechnology company with an extraordinary focus on tissue pathology and IHC. Spring's team of world-class researchers and scientists continually develop a carefully selected portfolio of antibodies that provides the histology community with strategic and effective antibody biomarkers for assessing protein expression in tissue.
Each Rabbit Monoclonal antibody is optimized for use with IHC and is put through a rigorous development and characterization process. The result is a sophisticated portfolio that easily pinpoints expression patterns of antibody targets across multiple tissue types.
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CISH gene amplification
The SPOT-Light® HER2 CISH Kit is intended for quantitative determination of HER2 gene amplification in formalin-fixed, paraffin embedded (FFPE) breast carcinoma tissue sections using chromogenic
in situ hybridization (CISH) and bright-field microscopy. This test should be performed in a histopathology laboratory.
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40% discount off on IL-18 kits
Interleukin 18 is a 18 kDa novel cytokine which is identified as a costimulatory factor for production of interferon-gamma in response to toxic shock. It shares functional similarities with IL-12. IL-18 is synthesized as a precursor 24kDa molecule without a signal peptide and must be cleaved to produce an active molecule. IL-1beta converting enzyme (ICE, Caspase-1) cleaves pro-IL-18 at aspartic acid in the P1 position, producting the mature, bioactive peptide that is readily released from the cells. It has been reported that IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon.
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Try an antibody for free!
Everest Biotech would like to invite all scientists to test the Aspiring antibodies in appropriate applications. Therefore they offer these products free of charge.
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PCR Inhibitors and Water RNA Isolation
Obtaining high quality RNA preps from any source is a challenge. However, isolating high quality RNA from turbid water smples is particularly challenging because of the high concentration of PCR inhibitors present in these samples. This challenge has been well documented:
As Dr. Darrell Chandler, environmental scientist at Akonni Biosystems Inc. (San Francisco) quoted in DDD mag "This is usually a bigger challenge than actually getting your hands on the RNA ittself".
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